New Report "Cell-Based Assays for Drug Discovery" available through Aarkstore Enterprise
09/08/2009

The area of drug discovery tools is one of the newest and most important sectors of pharmaceutical research and development.

Online PR News – 08-September-2009 – – The area of drug discovery tools is one of the newest and most important sectors of pharmaceutical research and development. The term drug discovery tools usually refers to high-content screening (HCS) and analysis and is composed of those applications that require sufficient levels of sample throughput, whereby complex cellular events and phenotypes can be studied. Elements of drug performance like toxicity and specificity can be established simultaneously using mixed cell types-primary cells, cell lines, cell subpopulations. HCS seeks to assess the impact of phenotypic and cellular changes that are brought about by gene modification (such as with RNA interference (RNAi) approaches) and/or drug (or compound) treatment. The purpose of this examination by TriMark Publications is to describe the specific segments of the global drug discovery tools market. Within this area, the report covers those segments that are highly active in terms of innovation and growth. Specifically, this study examines the markets for small lab equipment all the way up to highly automated, large automated platforms, as well as accessory equipment such as reagents, supplies and manufacturers' original equipment manufacturer (OEM) additional equipment.

Table of Contents :

1. Overview 4
1.1 Objectives of the Report 4
1.2 Methodology 5
1.3 Scope of the Report 6
1.4 Executive Summary 7

2. Technologies and Product Offering for High-Content Analysis 10
2.1 Definition of High-Content Analysis and Why it is so Attractive a Discipline 11
2.2 Classes of Measurements Possible with High-Content Analysis Approaches and Biologies Interrogated 14
2.3 Instrumentation Platforms for High-Content Analysis 17
2.3.1 High-Content Screening Technology 17
2.4 Reagent and Assay Platforms for High-Content Analysis 24
2.5 Cell-based Screening Technologies in Drug Development 28
2.5.1 Applications of Cell-based Assays 28
2.5.2 Pharma Drug Discovery Paradigm and Compound Screening 28
2.5.3 High-Content Analysis in the Biopharmaceutical Industry 29

3. Market Analysis of the High-Content Tools Space 31
3.1 High-Content Analysis Market Size and Growth 31
3.2 Market Survey to Assess Qualitative and Quantitative Parameters of the High-Content Analysis Space 31
3.3 Experimental and Research Trends in High-Content Analysis 33
3.4 Challenges and Market Drivers in High-Content Analysis 38
3.4.1 Barriers to High-Content Analysis 40
3.4.2 Drivers of High-Content Analysis 41
3.5 High-Content Analysis in Combination with RNAi 41
3.6 Market Landscape of Instrumentation for High-Content Analysis 43
3.7 Reagents and Assays Usage in High-Content Analysis 47
3.8 Trends in High-Content Analysis Assays/Reagents Space-Major Product Vendors 50
3.9 Emerging Market Trends in High-Content Analysis 52
3.10 Market Forecasts for the High-Content Analysis Space 54
3.11 Use of HCS in Pharmaceutical Companies 56
3.12 Qualitative Opportunities and Challenges for Market Adoption 57

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