PREMIER Biosoft announces the release of SimGlycanÂ® v. 5.0 to provide informatics support to Thermo Scientificâ„˘ LC-mass spectrometry (MS) methods.
Online PR News – 23-May-2014 – Palo Alto, California – PREMIER Biosoft, a next generation leader in bioinformatics today announced the release of a new version of SimGlycanÂ®, a comprehensive, high throughput tool to provide automated informatics support for LC-MS and MS/MS glycan data analysis workflows. The new version of the software facilitates processing of LC-MS and MS/MS data for peak detection, peak picking and alignment of glycans based on retention time, precursor m/z values, observed intensities across multiple samples.
According to Julian Saba, Senior Scientist at Thermo Scientificâ„˘, "Recent developments in mixedâ€“mode column chemistries and faster scanning mass spectrometers have increased the number of glycans resolved and identified by LC-MS workflows thereby delivering an unmatched analytical solution for glycan research. Our sophisticated workflows, along with SimGlycanÂ® as the informatics support, provide best-in-class glycan analysis. "
The newly developed glycomics workflow that features Thermo Scientificâ„˘ GlycanPacâ„˘ AXR-1 column coupled to a Thermo Scientificâ„˘ Orbitrapâ„˘ Fusionâ„˘ Tribrid mass spectrometer or Thermo ScientificTM Q ExactiveTM hybrid quadrupole-Orbitrap mass spectrometer enable resolution and identification of far more structures compared to other commercially available column technologies. However, the increase in peak resolution and detected compounds lead to large data sets. Manual deconvolution of complex chromatograms, identification of isotopic peaks, identifying MS/MS scans for detected compounds and selection of correct precursor m/z values from the isotope cluster for MS/MS data analysis is effectively incorporated in SimGlycanÂ®.
"As instruments get more sophisticated and aim to deliver highly accurate results, our effort is to upgrade the informatics support in the hands of the glycomics community to precisely interpret the new data analysis workflows supported by Thermo's instruments." said Arun Apte, CEO at PREMIER Biosoft.
About PREMIER Biosoft
Founded in 1994, is a group of computer scientists and biologists dedicated to producing cutting edge intuitive software for research in life sciences. Our goal is to study the most recent innovations in life sciences and translate them into software products to aid research.
More information is available at: http://www.premierbiosoft.com.