Intracytoplasmic sperm injection, or ICSI, is a technique developed to help achieve fertilization for couples with severe male factor infertility or couples who have had failure to fertilize in a previous in vitro fertilization attempt.
Online PR News – 18-October-2012 – New Delhi – Press Release
ICSI brings joy to childless family
New Delhi, 16th Oct: Intracytoplasmic sperm injection, or ICSI, is a technique developed to help achieve fertilization for couples with severe male factor infertility or couples who have had failure to fertilize in a previous in vitro fertilization attempt. The procedure overcomes many of the barriers to fertilization and allows couples with little hope of achieving successful pregnancy to obtain fertilized embryos.
According to Dr. D.K Jain, Infertility Specialist & Director of Adhinath Hospital, Indirapuram, Ghaziabad. The technique involves very precise maneuvers to pick up a single live sperm and inject it directly into the center of a human egg. The procedure requires that the female partner undergo ovarian stimulation with fertility medications so that several mature eggs develop (IVF). These eggs are then aspirated through the vagina, using vaginal ultrasound, and incubated under precise conditions in the embryology laboratory. The semen sample is prepared by centrifuging (spinning the sperm cells through a special medium). This solution separates live sperm from debris and most of the dead sperm. The embryologist picks up the single live sperm in a glass needle and injects it directly into the egg.
ICSI is considered absolutely necessary in the case of male factor infertility with an abnormal semen analysis. In the Bay Area, however approximately 75% of all IVF cases are now ICSI. Patients are electing to undergo ICSI for reasons other than male factor infertility. Those reasons include previous poor fertilization with IVF, variable sperm counts, and unexplained infertility. Thus, many patients choose to undergo the ICSI procedure to maximize their success even when the procedure may not be clearly indicated.
Through the ICSI procedure, many couples with difficult male factor infertility problems have achieved pregnancy at UCSF. Fertilization rates of 70-80% (of all eggs injected) equivalent to that of fertilization with normal sperm are currently being achieved and pregnancy rates are comparable to those seen with IVF in couples with no male factor infertility. The most important indicator of ICSI success appears to be the fertilization rate achieved with the ICSI procedure. The fertilization rate using our ICSI technique in the UCSF IVF laboratory is exceptional (currently 80-85%). That is to say, on average for every ten eggs, 8 eggs will fertilize normally. He added.
Dr. D.K Jain says, as with regular IVF, you’ll take ovarian stimulating drugs, while your doctor will monitor your progress with blood tests and ultrasounds. Once you’ve grown enough good-sized follicles, you’ll have the egg retrieval, where eggs are removed from your ovaries with a specialized, ultrasound-guided needle. Your partner will provide his sperm sample that same day (unless you’re using a sperm donor, or previously frozen sperm.) Once the eggs are retrieved, an embryologist will place the eggs in a special culture, and using a microscope and tiny needle, a single sperm will be injected into an egg. This will be done for each egg retrieved. If fertilization takes place, and the embryos are healthy, an embryo or two will be transferred to your uterus, via a catheter placed through the cervix, two to five days after the retrieval.
For further Information
Contact: Dr. D.K Jain