Oxford Expression Technologies Ltd (OET) and Trenzyme GmbH announce Bacmam Collaboration

Oxford Expression Technologies Ltd (OET) and Trenzyme GmbH, both experts in the field of recombinant protein expression have agreed to collaborate so that the full potential of their complementary technologies can be realized.

Online PR News – 02-March-2012 – – Oxford, United Kingdom /Konstanz, Germany, February 27, 2012 - Oxford Expression Technologies Ltd (OET) and Trenzyme GmbH, both experts in the field of recombinant protein expression have agreed to collaborate so that the full potential of their complementary technologies can be realized. Under terms of the collaboration, both companies will be able to offer a full range of recombinant protein expression services across a variety of platforms including baculovirus, yeast, bacterial and mammalian systems.

The collaboration offers exciting possibilities in the field of the rapidly developing BacMam system, in which baculoviruses are used for protein production in mammalian cell lines. The BacMam system increases the options available to improve both the yield and quality of recombinant proteins. It also has applications in therapeutic fields including the production of recombinant vaccines and gene delivery into human cells.

Furthermore, the BacMam system fits perfectly to the Cross Organism Expression platform of Trenzyme allowing the fast and reliable screening of the best expression host for a given target protein in respect of timelines, yield and quality.

Under the terms of the collaboration, customers of both companies will be able to access the complementary technologies.

Dr Richard Broadhead, Sales and Marketing Manager at OET commented, “At OET we always aim to maximize the potential of our flashBAC baculovirus expression system. The collaboration with Trenzyme will allow us to combine our patented technology with Trenzyme’s expression platform to expand the capabilities and applications of both. Working with Trenzyme will allow us to offer our customers additional options by working with a partner who is expert in other platforms for recombinant protein expression.”

Dr Reinhold Horlacher, managing director of Trenzyme commented, “We use our Cross Organism Expression platform to streamline expression projects with high demands on timeline, yield and protein quality – the simultaneous screening in up to four expression hosts using dozens of ready-to-use expression vectors will be significantly upvalued by embedding the BacMam system. We are happy to combine the innovative power of OET and Trenzyme to offer clients of both companies tailored solutions for recombinant protein expression”

OET is a biotechnology company specializing in recombinant protein expression and a recognised centre of excellence for baculovirus expression. Based in Oxford, UK, OET provides protein expression products, services and consultancy to the biotechnology and pharma community worldwide.

OET developed the patented, industry leading flashBAC® baculovirus expression system, and has expertise in applying the system to novel related fields such as virus like particle (VLP) production. OET has an active R&D programme to deliver further enhancements and capabilities to its expanding base of clients and partners.

Trenzyme is an ISO 9001 certified service provider offering customer specific solutions in the areas of molecular biology / bio-chemistry / generation of cell lines.

Trenzyme’s international clientele consists predominantly of pharmaceutical and biotech companies, for whom customized services have been provided successfully for more than 11 years.

Classical projects range from DNA cloning / gene synthesis by means of expression in different systems (E.coli, yeast, insect cells, mammal cells) to protein purification as well as development of stable mammalian cell lines.

Trenzyme is exclusively financed by private means and is constantly expanding its clientele. Over the last couple of years the company has experienced solid revenue growth.

Further Information is available at www.trenzyme.com

The statements in this press release that relate to future plans, events or performance are forward-looking statements that involve risks and uncertainties, including risks associated with uncertainties related to contract cancellations, developing risks, competitive factors, uncertainties pertaining to customer orders, demand for products and services, development of markets for the Company's products and services. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof. The Company undertakes no obligation to release publicly the result of any revisions to these forward-looking statements that may be made to reflect events or circumstances after the date hereof or to reflect the occurrence of unanticipated events.