BOC Sciences Offers Raw Chemical Materials for Manufacturing Test Kits and Vaccines
06/02/2020

Recently, BOC Sciences announced to offer raw chemical materials needed for the manufacture of test kits and vaccines.

Online PR News – 02-June-2020 – Shirley, NY – Recently, BOC Sciences, a New York-based chemical and pharmaceutical raw material supplier, announced to offer raw chemical materials needed for the manufacture of test kits and vaccines to meet the challenges facing the global pharmaceutical industry during the coronavirus outbreak.

Coronavirus detection reagents are essential for combating COVID-19, but they are in short supply in many countries of the world. Measures such as quarantine, contact tracing and social distancing are used to control the spread of coronavirus. However, if suspicious cases cannot be tested and identified, these measures have limited use. At present, the number of deaths due to coronaviruses is still rising, so the research and production of vaccines are also urgent.

The following test reagents provieded by BOC Sciences can be used in the production of COVID-19 test kits and vaccines:

2'-Deoxyadenosine-5'-monophosphate

2'-deoxyadenosine-5'-monophosphate is a derivative of AMP, which can be used to synthesize new photo-affinity tags for incorporation into DNA. Deoxyadenosine monophosphate (dAMP), also known as deoxyadenylic acid or deoxyadenylate in the forms of conjugate acids or conjugate bases, is a common nucleic acid AMP or adenosine monophosphate derivative.

2'-Deoxycytidine-5'-monophosphate

Deoxycytidine monophosphate (dCMP), also known as deoxycytidine or deoxycytidine, exists in the form of its conjugate acid or conjugate base, respectively. Deoxycytidine monophosphate is a deoxynucleotide, which is one of the four monomers that make up DNA. 2'-Deoxycytidine-5'-monophosphate is a deoxycytosine nucleotide containing one phosphate group esterified to the deoxyribose moiety in the 2'-,3'- or 5- positions. It belongs to the class of organic compounds known as pyrimidine 2'-deoxyribonucleoside monophosphates.

HEPES

HEPES (4- (2-hydroxyethyl) -1-piperazineethanesulfonic acid) is a zwitterionic sulfonic acid buffer. HEPES is like water, its decomposition decreases with decreasing temperature, which makes HEPES an effective buffer that can maintain the structure and function of enzymes at low temperatures. HEPES is widely used in cell culture. Hydrogen peroxide is generated when HEPES is exposed to ambient light, so it is best to keep HEPES-containing solutions in the dark to prevent oxidation.

Pseudouridine

Pseudouridine is the C5-glycoside isomer of uridine and is called the “fifth nucleoside” of RNA. It is the most abundant RNA modification in cellular RNA. Pseudouridine is commonly found in rRNA, tRNA and snRNA. They may also regulate RNA expression after transcription and play multiple roles in cells, including RNA translation, localization, and stabilization.

PEP-K

PEP-K (Phosphoenolpyruvic acid potassium salt), also known as alpha-ketopropionic acid, is a substrate for many kinase reactions. It is a white to pale yellow fine crystalline powder. PEP-K is involved in glycolysis and gluconeogenesis as a metabolic intermediate. It is used to regenerate ATP from ADP in enzyme-catalyzed synthesis. It is metabolized by pyruvate kinase to produce pyruvate. It prevents cell damage and dysfunction of carbohydrate metabolism caused by oxidative stress.

Guanidine hydrochloride

Guanidine hydrochloride is the hydrochloride form of guanidine. Guanidine hydrochloride is a widely used protein denaturant and can be used for the purification of proteins, nucleic acids, especially mRNA. It also has the ability to reduce enzyme activity and increase the solubility of hydrophobic molecules. Guanidine hydrochloride can enhance the release of acetylcholine after nerve impulses and enhance the effect of acetylcholine on muscarinic and nicotinic receptors.

For more information about the test reagents, please visit the website of BOC Sciences: https://www.bocsci.com/products/test-reagents-3302.html.

About BOC Sciences
With high-profiled experts specialized in multi-disciplines like drug discovery, chemistry and life science, BOC Sciences is a reliable vendor of a comprehensive collection of chemicals for scientists and researchers in both academia and industry. Over the last twenty years, it has gained a fame as well as valuable trust from customers worldwide in the supply of chemicals like small molecule inhibitors, APIs, pharmaceutical excipients, intermediates and natural compounds. In addition, it also provides all-stage-covering drug R&D services to support the pharmaceutical industry.